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NDUFA4L2 Regulated by HIF-1α Promotes Metastasis and Epithelial–Mesenchymal Transition of Osteosarcoma Cells Through Inhibiting ROS Production

Osteosarcoma (OS) accounts for a large proportion of the types of bone tumors that are newly diagnosed, and is a relatively common bone tumor. However, there are still no effective treatments for this affliction. One interesting avenue is related to the mitochondrial NDUFA4L2 protein, which is encod...

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Detalles Bibliográficos
Autores principales: Xu, Wen-Ning, Yang, Run-Ze, Zheng, Huo-Liang, Jiang, Lei-Sheng, Jiang, Sheng-Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714780/
https://www.ncbi.nlm.nih.gov/pubmed/33330441
http://dx.doi.org/10.3389/fcell.2020.515051