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Cytotoxic T Cell Responses Induced by CS1/CRT Fusion DNA Vaccine in a Human Plasmacytoma Model

To date, multiple myeloma remains an incurable disease. Immunotherapy is an encouraging option in the development of multiple myeloma (MM) therapy. CS1 is a specific myeloma antigen, which is highly expressed in myeloma cells. Calreticulin (CRT) is a key determinant of cell death, which can influenc...

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Detalles Bibliográficos
Autores principales: Ye, Xueshi, Li, Wanli, Huang, Jinwen, Zhang, Lifei, Zhang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714938/
https://www.ncbi.nlm.nih.gov/pubmed/33330069
http://dx.doi.org/10.3389/fonc.2020.587237