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The role of tumor-associated macrophages (TAMs) in tumor progression and relevant advance in targeted therapy
Macrophages have a leading position in the tumor microenvironment (TME) which paves the way to carcinogenesis. Initially, monocytes and macrophages are recruited to the sites where the tumor develops. Under the guidance of different microenvironmental signals, macrophages would polarize into two fun...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714989/ https://www.ncbi.nlm.nih.gov/pubmed/33304783 http://dx.doi.org/10.1016/j.apsb.2020.04.004 |