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Alzheimer Cells on Their Way to Derailment Show Selective Changes in Protein Quality Control Network

Alzheimer’s Disease is driven by protein aggregation and is characterized by accumulation of Tau protein into neurofibrillary tangles. In healthy neurons the cellular protein quality control is successfully in charge of protein folding, which raises the question to which extent this control is distu...

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Detalles Bibliográficos
Autores principales: Koopman, Margreet B., Rüdiger, Stefan G. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715003/
https://www.ncbi.nlm.nih.gov/pubmed/33330614
http://dx.doi.org/10.3389/fmolb.2020.00214