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Alzheimer Cells on Their Way to Derailment Show Selective Changes in Protein Quality Control Network
Alzheimer’s Disease is driven by protein aggregation and is characterized by accumulation of Tau protein into neurofibrillary tangles. In healthy neurons the cellular protein quality control is successfully in charge of protein folding, which raises the question to which extent this control is distu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715003/ https://www.ncbi.nlm.nih.gov/pubmed/33330614 http://dx.doi.org/10.3389/fmolb.2020.00214 |