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Conjugation of Synthetic Polyproline Moietes to Lipid II Binding Fragments of Nisin Yields Active and Stable Antimicrobials

Coupling functional moieties to lantibiotics offers exciting opportunities to produce novel derivatives with desirable properties enabling new functions and applications. Here, five different synthetic hydrophobic polyproline peptides were conjugated to either nisin AB (the first two rings of nisin)...

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Detalles Bibliográficos
Autores principales: Deng, Jingjing, Viel, Jakob H., Kubyshkin, Vladimir, Budisa, Nediljko, Kuipers, Oscar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715017/
https://www.ncbi.nlm.nih.gov/pubmed/33329435
http://dx.doi.org/10.3389/fmicb.2020.575334