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Conjugation of Synthetic Polyproline Moietes to Lipid II Binding Fragments of Nisin Yields Active and Stable Antimicrobials
Coupling functional moieties to lantibiotics offers exciting opportunities to produce novel derivatives with desirable properties enabling new functions and applications. Here, five different synthetic hydrophobic polyproline peptides were conjugated to either nisin AB (the first two rings of nisin)...
Autores principales: | Deng, Jingjing, Viel, Jakob H., Kubyshkin, Vladimir, Budisa, Nediljko, Kuipers, Oscar P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715017/ https://www.ncbi.nlm.nih.gov/pubmed/33329435 http://dx.doi.org/10.3389/fmicb.2020.575334 |
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