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Mechanistic Insights Into the Reduced Pacemaking Rate of the Rabbit Sinoatrial Node During Postnatal Development: A Simulation Study

Marked age- and development- related differences have been observed in morphology and characteristics of action potentials (AP) of neonatal and adult sinoatrial node (SAN) cells. These may be attributable to a different set of ion channel interactions between the different ages. However, the underly...

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Detalles Bibliográficos
Autores principales: Alghamdi, Azzah M., Testrow, Craig P., Whittaker, Dominic G., Boyett, Mark R., Hancox, Jules. C., Zhang, Henggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715043/
https://www.ncbi.nlm.nih.gov/pubmed/33329016
http://dx.doi.org/10.3389/fphys.2020.547577