Cargando…
Mechanistic Insights Into the Reduced Pacemaking Rate of the Rabbit Sinoatrial Node During Postnatal Development: A Simulation Study
Marked age- and development- related differences have been observed in morphology and characteristics of action potentials (AP) of neonatal and adult sinoatrial node (SAN) cells. These may be attributable to a different set of ion channel interactions between the different ages. However, the underly...
Autores principales: | Alghamdi, Azzah M., Testrow, Craig P., Whittaker, Dominic G., Boyett, Mark R., Hancox, Jules. C., Zhang, Henggui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715043/ https://www.ncbi.nlm.nih.gov/pubmed/33329016 http://dx.doi.org/10.3389/fphys.2020.547577 |
Ejemplares similares
-
The Functional Role of Hyperpolarization Activated Current (I(f)) on Cardiac Pacemaking in Human vs. in the Rabbit Sinoatrial Node: A Simulation and Theoretical Study
por: Bai, Xiangyun, et al.
Publicado: (2021) -
Modeling the Chronotropic Effect of Isoprenaline on Rabbit Sinoatrial Node
por: Zhang, Henggui, et al.
Publicado: (2012) -
Cardiac Pacemaker Dysfunction Arising From Different Studies of Ion Channel Remodeling in the Aging Rat Heart
por: Alghamdi, Aaazh M., et al.
Publicado: (2020) -
Drivers of Sinoatrial Node Automaticity in Zebrafish: Comparison With Mechanisms of Mammalian Pacemaker Function
por: Stoyek, Matthew R., et al.
Publicado: (2022) -
In silico Assessment of Pharmacotherapy for Human Atrial Patho-Electrophysiology Associated With hERG-Linked Short QT Syndrome
por: Whittaker, Dominic G., et al.
Publicado: (2019)