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Injectable thermo-responsive nano-hydrogel loading triptolide for the anti-breast cancer enhancement via localized treatment based on “two strikes” effects

The clinical application of triptolide (TPL) in tumor therapy has been greatly limited by its toxicity and inefficient delivery. Herein, a localized and sustained-release thermo-sensitive hydrogel was developed for the intra-tumor administration of TPL. Based on the amphiphilic structure of poly (N-...

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Detalles Bibliográficos
Autores principales: Luo, Yaoyao, Li, Jingjing, Hu, Yichen, Gao, Fei, Pak-Heng Leung, George, Geng, Funeng, Fu, Chaomei, Zhang, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715064/
https://www.ncbi.nlm.nih.gov/pubmed/33304788
http://dx.doi.org/10.1016/j.apsb.2020.05.011