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Injectable thermo-responsive nano-hydrogel loading triptolide for the anti-breast cancer enhancement via localized treatment based on “two strikes” effects
The clinical application of triptolide (TPL) in tumor therapy has been greatly limited by its toxicity and inefficient delivery. Herein, a localized and sustained-release thermo-sensitive hydrogel was developed for the intra-tumor administration of TPL. Based on the amphiphilic structure of poly (N-...
Autores principales: | Luo, Yaoyao, Li, Jingjing, Hu, Yichen, Gao, Fei, Pak-Heng Leung, George, Geng, Funeng, Fu, Chaomei, Zhang, Jinming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715064/ https://www.ncbi.nlm.nih.gov/pubmed/33304788 http://dx.doi.org/10.1016/j.apsb.2020.05.011 |
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