MBRS-67. ROLE OF CYCLIN DEPENDENT KINASE-9 IN Myc-ENHANCED MEDULLOBLASTOMA

Myc is highly expressed in group 3 medulloblastoma (Myc-MB) and influences cell growth, proliferation and oncogenesis by directly promoting the activity of RNA polymerases (RNA Pol). Myc driven RNA Pol II activity is mediated by Positive Transcription Elongation Factor b (pTEFb). pTEFb’s catalytic c...

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Detalles Bibliográficos
Autores principales: Madhavan, Krishna, Veo, Bethany, Danis, Etienne, Balakrishnan, Ilango, Pierce, Angela, Wang, Dong, Abdel-Hafiz, Ahmed, Serkova, Natalie, Dahl, Nathan, Venkataraman, Sujatha, Vibhakar, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Medulloblastoma (Research)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715077/
http://dx.doi.org/10.1093/neuonc/noaa222.571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715077/
http://dx.doi.org/10.1093/neuonc/noaa222.571

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