RARE-19. PEDIATRIC HIGH GRADE GLIOMA WITH DNA REPAIR PATHWAY ABERRATIONS, CLINICAL CHARACTERISTICS AND OUTCOME

DNA mismatch repair machinery is an integral part of the human genome and its defect has been involved in tumorigenesis and treatment resistance. Heterozygous monoallelic germline loss of function in MLH-1, MSH-2, MSH-6 or PMS-2 is involved in Lynch syndrome, whereas biallelic mutations cause consti...

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Detalles Bibliográficos
Autores principales: Baig, Muhammad, McCall, David, Moss, Tyler, Sandberg, David, Fuller, Gregory, McGovern, Susan, Paulino, Arnold, Najjar, Amer, Chandra, Joya, Khatua, Soumen, Zaky, Wafik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Craniopharyngioma and Rare Tumors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715083/
http://dx.doi.org/10.1093/neuonc/noaa222.730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715083/
http://dx.doi.org/10.1093/neuonc/noaa222.730

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