MBRS-54. POOR SURVIVAL IN REPLICATION REPAIR DEFICIENT HYPERMUTANT MEDULLOBLASTOMA AND CNS EMBRYONAL TUMORS: A REPORT FROM THE INTERNATIONAL RRD CONSORTIUM

BACKGROUND: Mutations in mismatch repair (MMR) and DNA-polymerase (POL) genes lead to DNA replication repair deficiency (RRD), resulting in a growing group of previously under-recognized childhood brain tumors. Medulloblastoma and embryonal tumors are rarely reported in RRD. Their biological and cli...

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Detalles Bibliográficos
Autores principales: Das, Anirban, Bianchi, Vanessa, Edwards, Melissa, Varghese, Nobish, Sudhaman, Sumedha, Farah, Roula, Dvir, Rina, Reddy, Alyssa, Raskin, Salmo, Hansford, Jordan, Hamid, Syed Ahmer, Hsu, Saunders, Yen, Lee Yi, Quider, Abed Abu, Ghalibafian, Mithra, Koustenis, Elisabeth, Al-Battashi, Abeer, Mason, Gary, Lee, Joung, Bell, Danille, Stearns, Duncan, Ziegler, David, Zapotocky, Michal, Lasaletta, Alvaro, Kulkarni, Abhaya, Tsang, Derek S, Laperriere, Normand, Hawkins, Cynthia, Bouffet, Eric, Ramaswamy, Vijay, Tabori, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Medulloblastoma (Research)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715111/
http://dx.doi.org/10.1093/neuonc/noaa222.560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715111/
http://dx.doi.org/10.1093/neuonc/noaa222.560

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