DDEL-05. BLOOD-BRAIN BARRIER DISRUPTION AND ENHANCED RADIOSENSITIZERS EXTRAVASATION UPON FOCUSED ULTRASOUND FOR TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA

Poor prognosis of diffuse midline glioma, including diffuse intrinsic pontine glioma (DIPG), reflects the low efficacy of current treatment strategies, mainly due to (1) a largely intact blood-brain barrier (BBB) and (2) the proficiency of tumour tissues to upregulate multiple DNA repair genes, resu...

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Detalles Bibliográficos
Autores principales: Hart, Elvin ‘t, Derieppe, Marc, Bruin, Maaike, Besse, Helena, Haumann, Rianne, Hoving, Eelco, Huitema, Alwin, Ries, Mario, van Vuurden, Dannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Drug Delivery/Pharmacokinetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715181/
http://dx.doi.org/10.1093/neuonc/noaa222.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715181/
http://dx.doi.org/10.1093/neuonc/noaa222.040

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