HGG-20. DIAGNOSTIC AND BIOLOGICAL ROLE OF METHYLATION PATTERNS IN REPLICATION REPAIR DEFICIENT HIGH GRADE GLIOMAS

Replication repair deficiency (RRD) is an important driving mechanism of pediatric high grade glioma (pHGG) occurring predominantly in the context of germline mutations in RRD-associated genes. Although pHGG present specific patterns of DNA methylation corresponding to driving oncogenic processes, m...

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Detalles Bibliográficos
Autores principales: Dodgshun, Andrew, Fukuoka, Kohei, Edwards, Melissa, Bianchi, Vanessa, Sexton-Oates, Alexandra, Larouche, Valerie, Magimairajan, Vanan, Lindhorst, Scott, Yalon, Michal, Mason, Gary, Crooks, Bruce, Constantini, Shlomi, Massimino, Maura, Chiaravalli, Stefano, Ramdas, Jagadeesh, Mason, Warren, Shamvil, Ashraf, Farah, Roula, Van Damme, An, Opocher, Enrico, Hamid, Syed Ahmer, Ziegler, David, Samuel, David, Cole, Kristina A, Tomboc, Patrick, Stearns, Duncan, Thomas, Gregory, Lossos, Alexander, Sullivan, Michael, Hansford, Jordan R, Jones, David, Mackay, Alan, Jones, Chris, Ramaswamy, Vijay, Hawkins, Cynthia, Bouffet, Eric, Tabori, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
High Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715189/
http://dx.doi.org/10.1093/neuonc/noaa222.307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715189/
http://dx.doi.org/10.1093/neuonc/noaa222.307

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