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DIPG-64. INTERNATIONAL PRECLINICAL DRUG DISCOVERY AND BIOMARKER PROGRAM INFORMING AN ADOPTIVE COMBINATORIAL TRIAL FOR DIFFUSE MIDLINE GLIOMAS

INTRODUCTION: DMG-ACT (DMG- multi-arm Adaptive and Combinatorial Trial) aims to implement a highly innovative clinical trial design of combinatorial arms for patients with diffuse midline gliomas (DMGs) at all disease stages that is adaptive to pre-clinical data generated in eight collaborating inst...

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Detalles Bibliográficos
Autores principales: Przystal*, Justyna M, Yadavilli*, Sridevi, Abadi*, Christina Colman, Yadav, Viveka Nand, Laternser, Sandra, Cosentino, Chiara Cianciolo, Waszak, Sebastian M, Cartaxo, Rodrigo, Biery, Matt, Myers, Carrie, Jayasekara, Samantha, Olson, James M, Filbin, Mariella G, Vitanza, Nicholas A, Cain, Jason, Koschmann#, Carl, Müller#, Sabine, Nazarian#, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715218/
http://dx.doi.org/10.1093/neuonc/noaa222.109