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HGG-41. STRUCTURAL VARIANT DRIVERS IN PEDIATRIC HIGH-GRADE GLIOMA

BACKGROUND: Driver single nucleotide variants (SNV) and somatic copy number aberrations (SCNA) of pediatric high-grade glioma (pHGGs), including Diffuse Midline Gliomas (DMGs) are characterized. However, structural variants (SVs) in pHGGs and the mechanisms through which they contribute to glioma fo...

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Detalles Bibliográficos
Autores principales: Dubois, Frank, Shapira, Ofer, Greenwald, Noah, Zack, Travis, Tsai, Jessica W, Harutyunyan, Ashot S, Kumar, Kiran, Sinai, Claire, Malkin, Hayley, Jones, Robert, Ho, Patricia, O’Rourke, Ryan, Kang, Kyung S, Jabado, Nada, Kieran, Mark W, Ligon, Keith, Beroukhim, Rameen, Bandopadhayay, Pratiti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715247/
http://dx.doi.org/10.1093/neuonc/noaa222.322