DIPG-11. A PHASE I DOSE ESCALATION STUDY OF BXQ-350 IN CHILDREN AND YOUNG ADULTS WITH RELAPSED SOLID TUMORS

BXQ-350 is a novel agent composed of the multifunctional, lysosomal activator protein Saposin C (SapC) and dioleoyl- phosphatidylserine (DOPS). BXQ-350 demonstrated antitumor effects in vitro and in vivo. Many tumors, including diffuse intrinsic pontine glioma (DIPG), and cells of tumor vasculature...

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Detalles Bibliográficos
Autores principales: Setty, Bhuvana, Cripe, Timothy, Schottmiller, Mariko DeWire-, Curry, Richard, AdelBaki, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Diffuse Midline Glioma/DIPG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715257/
http://dx.doi.org/10.1093/neuonc/noaa222.061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715257/
http://dx.doi.org/10.1093/neuonc/noaa222.061

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