DIPG-34. SUPER ELONGATION COMPLEX AS A TARGETABLE DEPENDENCY IN H3K27M+ DIFFUSE MIDLINE GLIOMA

Mutations in the histone 3 gene (H3K27M) are the eponymous driver in diffuse intrinsic pontine gliomas (DIPGs) and other diffuse midline gliomas (DMGs), aggressive pediatric brain tumors for which no curative therapy currently exists. To identify specific epigenetic dependencies within the context o...

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Detalles Bibliográficos
Autores principales: Dahl, Nathan, Danis, Etienne, Balakrishnan, Ilango, Wang, Dong, Pierce, Angela, Walker, Faye, Gilani, Ahmed, Serkova, Natalie, Madhaven, Krishna, Fosmire, Susan, Green, Adam, Foreman, Nicholas, Venkataraman, Sujatha, Vibhakar, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Diffuse Midline Glioma/DIPG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715266/
http://dx.doi.org/10.1093/neuonc/noaa222.082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715266/
http://dx.doi.org/10.1093/neuonc/noaa222.082

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