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IMMU-15. PROTEOGENOMIC DISCOVERY OF NOVEL TUMOR PEPTIDES AS NEOANTIGENS FOR PERSONALIZED T CELL IMMUNOTHERAPY IN MEDULLOBLASTOMA

T cell immunotherapies are promising new tools to combat high-risk subgroups of medulloblastoma without increasing the late effects burden. The ideal target antigen of an effective antitumor T-cell response is abundantly expressed by tumor cells but not by normal tissues, in order to limit off-targe...

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Detalles Bibliográficos
Autores principales: Rivero-Hinojosa, Samuel, Grant, Melanie, Panigrahi, Aswini, Zhang, Huizhen, Caisova, Veronika, Bollard, Catherine, Rood, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715278/
http://dx.doi.org/10.1093/neuonc/noaa222.371