MODL-29. EVALUATING TUMOR-IMMUNE INTERACTIONS IN MOUSE MODELS OF DIFFUSE INTRINSIC PONTINE GLIOMA

BACKGROUND: While adult gliomas show some level of immune cell infiltration, diffuse intrinsic pontine glioma (DIPG) is characterized as having an “immune cold” state. We have developed new immunocompetent mouse models of DIPG. These models faithfully recapitulate the pathological hallmarks of DIPG...

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Detalles Bibliográficos
Autores principales: Furnish, Robin, Bear, Heather, Wei, Xin, Phoenix, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Preclinical Models/Experimental Therapy/Drug Discovery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715296/
http://dx.doi.org/10.1093/neuonc/noaa222.602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715296/
http://dx.doi.org/10.1093/neuonc/noaa222.602

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