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MBRS-60. THE ACTIONABLE GENOMIC LANDSCAPE OF RELAPSED MEDULLOBLASTOMA IS DEFINED BY MAINTENANCE AND ACQUISITION OF DRIVER EVENTS

Medulloblastoma relapse (rMB) occurs in 30–40% of patients and is almost universally fatal. Understanding the genomic landscape of rMB, and its relationship to disease characteristics at diagnosis, will be essential to underpin the development of improved therapeutic strategies, delivered at both di...

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Detalles Bibliográficos
Autores principales: Richardson, Stacey, Hill, Rebecca M, Kui, Christopher, Lindsey, Janet C, Grabovska, Yura, Schwalbe, Edward C, Hicks, Debbie, Williamson, Daniel, Crosier, Stephen, Joshi, Abjhit, Wharton, Stephen B, Hansford, Jordan, Pizer, Barry, Vinci, Maria, Mastronuzzi, Angela, Carai, Andrea, Michalski, Anthony, Jacques, Thomas S, Bailey, Simon, Clifford, Steven C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715322/
http://dx.doi.org/10.1093/neuonc/noaa222.564