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DIPG-21. INDUCTION OF MITOTIC ABNORMALITIES AND BMI-1 MODULATION TO TREAT DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse intrinsic pontine glioma (DIPG) is a poor-prognosis pediatric brain tumor with a median survival of less than one year. No effective therapy is currently available, and no therapeutic advances have been made in several decades. BMI-1 is a member of the multimeric protein complex Polycomb rep...

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Detalles Bibliográficos
Autores principales: Kumar, Shiva Senthil, Sengupta, Satarupa, Zhu, Xiaoting, Mishra, Deepak Kumar, Fuller, Christine, Fouladi, Maryam, Drissi, Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715380/
http://dx.doi.org/10.1093/neuonc/noaa222.071