HGG-07. CYCLIN-DEPENDENT KINASES AS TARGET STRUCTURES FOR CANCER THERAPY – A COMPARATIVE IN VITRO ANALYSIS ON PATIENT-DERIVED GLIOBLASTOMA CELL CULTURE MODELS

INTRODUCTION: Current therapeutic approaches have limited clinical success for Glioblastoma patients, making novel strategies urgent. Cyclin-dependent kinases (CDK) are crucial in cell cycle, oncogenic transcription, DNA repair, and stem-cell renewal. Glioma cells frequently show genomic alterations...

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Detalles Bibliográficos
Autores principales: Riess, Christin, Classen, Carl Friedrich, Maletzki, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
High Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715447/
http://dx.doi.org/10.1093/neuonc/noaa222.298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715447/
http://dx.doi.org/10.1093/neuonc/noaa222.298

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