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Molecular engineering of antibodies for site-specific conjugation to lipid polydopamine hybrid nanoparticles

Conjugation of antibodies to nanoparticles allows specific cancer targeting, but conventional conjugation methods generate heterogeneous conjugations that cannot guarantee the optimal orientation and functionality of the conjugated antibody. Here, a molecular engineering technique was used for site-...

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Detalles Bibliográficos
Autores principales: Yang, Hobin, Le, Quoc-Viet, Shim, Gayong, Oh, Yu-Kyoung, Shin, Young Kee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715496/
https://www.ncbi.nlm.nih.gov/pubmed/33304787
http://dx.doi.org/10.1016/j.apsb.2020.07.006