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Molecular engineering of antibodies for site-specific conjugation to lipid polydopamine hybrid nanoparticles
Conjugation of antibodies to nanoparticles allows specific cancer targeting, but conventional conjugation methods generate heterogeneous conjugations that cannot guarantee the optimal orientation and functionality of the conjugated antibody. Here, a molecular engineering technique was used for site-...
Autores principales: | Yang, Hobin, Le, Quoc-Viet, Shim, Gayong, Oh, Yu-Kyoung, Shin, Young Kee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715496/ https://www.ncbi.nlm.nih.gov/pubmed/33304787 http://dx.doi.org/10.1016/j.apsb.2020.07.006 |
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