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TBIO-26. NON-CANONICAL OPEN READING FRAMES ENCODE FUNCTIONAL PROTEINS ESSENTIAL FOR CANCER CELL SURVIVAL

The brain is the foremost non-gonadal tissue for expression of non-coding RNAs of unclear function. Yet, whether such transcripts are truly non-coding or rather the source of non-canonical protein translation is unknown. Here, we used functional genomic screens to establish the cellular bioactivity...

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Detalles Bibliográficos
Autores principales: Prensner, John, Enache, Oana, Luria, Victor, Krug, Karsten, Clauser, Karl, Dempster, Joshua, Karger, Amir, Wang, Li, Stumbraite, Karolina, Wang, Vickie, Botta, Ginevra, Lyons, Nicholas, Goodale, Amy, Kalani, Zohra, Fritchman, Briana, Brown, Adam, Alan, Douglas, Green, Thomas, Yang, Xiaoping, Jaffe, Jacob, Roth, Jennifer, Piccioni, Federica, Kirschner, Marc, Ji, Zhe, Root, David, Golub, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715501/
http://dx.doi.org/10.1093/neuonc/noaa222.849