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DIPG-42. TOWARD MULTIMODALITY THERAPY FOR DIPG/DMG: DEVELOPMENT AND INVESTIGATION OF CRANIOSPINAL IRRADIATION AND CONVECTION-ENHANCED DELIVERY PDX MODELS

BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) and diffuse midline glioma (DMG) are metastatic diseases, as demonstrated by early convection-enhanced delivery (CED) clinical trials in which prolonged local tumor control can sometimes be achieved, but fatal disseminated disease then develops. We...

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Detalles Bibliográficos
Autores principales: Knox, Aaron J, Gilani, Ahmed, van Court, Benjamin, Oweida, Ayman, Flannery, Patrick, DeSisto, John, Lemma, Rakeb, Chatwin, Hannah, Gamboni, Fabia, Brown, Benjamin, Serkova, Natalie, Vibhakar, Rajeev, Dorris, Kathleen, Wempe, Michael, Reisz, Julie A, Karam, Sana D, Green, Adam L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715556/
http://dx.doi.org/10.1093/neuonc/noaa222.089