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DIPG-42. TOWARD MULTIMODALITY THERAPY FOR DIPG/DMG: DEVELOPMENT AND INVESTIGATION OF CRANIOSPINAL IRRADIATION AND CONVECTION-ENHANCED DELIVERY PDX MODELS
BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) and diffuse midline glioma (DMG) are metastatic diseases, as demonstrated by early convection-enhanced delivery (CED) clinical trials in which prolonged local tumor control can sometimes be achieved, but fatal disseminated disease then develops. We...
Autores principales: | Knox, Aaron J, Gilani, Ahmed, van Court, Benjamin, Oweida, Ayman, Flannery, Patrick, DeSisto, John, Lemma, Rakeb, Chatwin, Hannah, Gamboni, Fabia, Brown, Benjamin, Serkova, Natalie, Vibhakar, Rajeev, Dorris, Kathleen, Wempe, Michael, Reisz, Julie A, Karam, Sana D, Green, Adam L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715556/ http://dx.doi.org/10.1093/neuonc/noaa222.089 |
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