DIPG-83. USING COPPER CHELATING AGENTS TO TARGET RECEPTOR TYROSINE KINASE SIGNALLING IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

DIPG is a universally fatal pediatric brain cancer. Receptor tyrosine kinase (RTK) pathway alterations are among the defining characteristics in many patients. Copper is a transition metal essential for cellular signaling, known to impact PI3K/AKT and MAPK/ERK pathways. Copper chelating agents are c...

Descripción completa

Detalles Bibliográficos
Autores principales: Michniewicz, Filip, Saletta, Federica, Rouen, Jourdin, Ziegler, David, Vittorio, Orazio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Diffuse Midline Glioma/DIPG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715651/
http://dx.doi.org/10.1093/neuonc/noaa222.124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715651/
http://dx.doi.org/10.1093/neuonc/noaa222.124

Ejemplares similares