IMMU-06. T-CELL IMMUNOTHERAPY FOR PEDIATRIC BRAIN TUMORS: DIVERSITY IN CELL SURFACE ANTIGEN AND HLA EXPRESSION NECESSITATES A MULTI-PRONGED APPROACH

Cell surface or intracellular antigens expressed in pediatric brain tumors are potential targets for chimeric antigen receptor (CAR) or ab (T-cell receptor) TCR T-cell immunotherapy. At present it remains unknown what cell surface antigens are suitable CAR targets for pediatric brain tumors; in addi...

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Detalles Bibliográficos
Autores principales: Houke, Haley, Zhu, Xiaoyan, Mercer, Kimberly S, Stripay, Jennifer L, Chiang, Jason, Baker, Suzanne J, Roussel, Martine F, Gottschalk, Stephen, Krenciute, Giedre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715662/
http://dx.doi.org/10.1093/neuonc/noaa222.362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715662/
http://dx.doi.org/10.1093/neuonc/noaa222.362

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