RARE-07. THE LANDSCAPE OF GENOMIC ALTERATIONS IN ADAMANTINOMATOUS CRANIOPHARYNGIOMAS

INTRODUCTION: Adamantinomatous craniopharyngiomas (ACPs) are characterized by activating mutations in the CTNNB1 gene. Here we perform a comprehensive genomic analysis of 23 ACPs to define the landscape of genomic alterations in this disease. METHODS: We performed whole-genome sequencing of 24 ACPs...

Descripción completa

Detalles Bibliográficos
Autores principales: Khadka, Prasidda, Prince, Eric, Lu, Sophie, Santagata, Sandro, Ligon, Keith, Manley, Peter, Beroukhim, Rameen, Hankinson, Todd, Bandopadhayay, Pratiti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Craniopharyngioma and Rare Tumors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715698/
http://dx.doi.org/10.1093/neuonc/noaa222.718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715698/
http://dx.doi.org/10.1093/neuonc/noaa222.718

Ejemplares similares