NFB-06. TREATMENT CHALLENGES IN PEDIATRIC GLIOBLASTOMA MULTIFORME WITH CONCURRENT SOMATIC AND GERMLINE NF1 MUTATIONS WITH GERMLINE MISMATCH REPAIR MUTATIONS: TWO UNIQUE CASES

INTRODUCTION: We report the first known cases of pediatric glioblastoma (GBM) with prior clinical NF1 diagnoses, one with concurrent germline Lynch syndrome (LS) and NF1, and the other with somatic NF1 mutation and germline constitutional mismatch repair deficiency (CMMRD). METHODS: Two pediatric GB...

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Detalles Bibliográficos
Autores principales: Baig, Muhammed, Mork, Maureen, Khatua, Soumen, Slopis, John, Zaky, Wafik, Bingham, Racheal, Gupta, Sumit, Fuller, Greg, Sadighi, Zsila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Neurofibromatosis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715720/
http://dx.doi.org/10.1093/neuonc/noaa222.610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715720/
http://dx.doi.org/10.1093/neuonc/noaa222.610

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