MODL-23. DNA METHYLATION AND COPY NUMBER VARIATION PROFILE FOR CHARACTERIZATION OF PEDIATRIC BRAIN TUMOR PRIMARY CELL LINES

BACKGROUND: In vitro models of pediatric brain tumors (pBT) are instrumental for both understanding the oncogenic molecular mechanisms and identifying/testing new therapeutic strategies. DNA methylation (DM) is a stable epigenetic modification recently used to classify tumors. We aim to apply DM and...

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Detalles Bibliográficos
Autores principales: Pedace, Lucia, Vinci, Maria, Pizzi, Simone, Pericoli, Giulia, Catanzaro, Giuseppina, Abballe, Luana, Del Bufalo, Francesca, Caruana, Ignazio, Camassei, Francesca Diomedi, Rossi, Sabrina, Giangaspero, Felice, Ferretti, Elisabetta, Ciolfi, Andrea, Tartaglia, Marco, Locatelli, Franco, Mastronuzzi, Angela, Miele, Evelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Preclinical Models/Experimental Therapy/Drug Discovery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715739/
http://dx.doi.org/10.1093/neuonc/noaa222.596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715739/
http://dx.doi.org/10.1093/neuonc/noaa222.596

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