EPCT-13. CMV PP65 RNA-PULSED DENDRITIC CELL VACCINES FOR PEDIATRIC GLIOBLASTOMA AND MEDULLOBLASTOMA: PHASE I TRIAL RESULTS

BACKGROUND: Recurrent medulloblastoma and malignant glioma are lethal tumors that are virtually incurable. The cytomegalovirus (CMV) antigen pp65 is ubiquitously expressed on medulloblastoma and malignant glioma but not on healthy brain. We evaluated autologous CMV pp65 RNA-pulsed dendritic cell (DC...

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Detalles Bibliográficos
Autores principales: Landi, Daniel, Archer, Gary, Driscoll, Timothy, Lipp, Eric, Archambault, Bridget, Thompson, Eric, Flahiff, Charlene, Jaggers, Denise, Hahn, Kathleen, Healy, Patrick, Ramirez, Luis, Herndon, James, Schroeder, Kristin, Sampson, John, Ashley, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Early Phase Clinical Trials
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715746/
http://dx.doi.org/10.1093/neuonc/noaa222.136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715746/
http://dx.doi.org/10.1093/neuonc/noaa222.136

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