IMMU-14. IMMUNE CHECKPOINT INHIBITOR THERAPY FOR TREATMENT OF SYNCHRONOUS CANCERS IN PAEDIATRIC PATIENTS WITH CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY

Constitutional mismatch repair deficiency (CMMRD) is an autosomal recessive condition in which affected patients carry biallelic germline mutations in the MMR genes. This highly penetrant syndrome results in nearly universal development of malignant neoplasms at a young age, most commonly pediatric...

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Detalles Bibliográficos
Autores principales: Henderson, Jacob, Morgenstern, Daniel, Edwards, Melissa, Sudhaman, Sumedha, Kram, David, Osborn, Michael, Cho, Yoon-Jae, Tabori, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715753/
http://dx.doi.org/10.1093/neuonc/noaa222.370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715753/
http://dx.doi.org/10.1093/neuonc/noaa222.370

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