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IMG-21. PROSPECTIVE PREOPERATIVE DETERMINATION OF ISOCITRATE DEHYDROGENASE MUTATION IN GLIOMAS USING SPECTRAL EDITING MAGNETIC RESONANCE SPECTROSCOPY

BACKGROUND: Gliomas are the most common malignant brain tumors in children and adults. A subset of these tumors harbour mutations in the enzyme isocitrate dehydrogenase (IDH) which produces the novel oncometabolite 2-hydroxyglutarate (2HG). In general, patients with an IDH mutant glioma have a longe...

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Detalles Bibliográficos
Autores principales: Nguyen, Thanh, Melkus, Gerd, Taccone, Michael, Ghinda, Diana, Torres, Carlos, Zakhari, Nader, Woulfe, John, Jansen, Gerrard, Cameron, Ian, Moldovan, Ioana, Alkherayf, Fahad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715783/
http://dx.doi.org/10.1093/neuonc/noaa222.356