Cargando…
IMG-21. PROSPECTIVE PREOPERATIVE DETERMINATION OF ISOCITRATE DEHYDROGENASE MUTATION IN GLIOMAS USING SPECTRAL EDITING MAGNETIC RESONANCE SPECTROSCOPY
BACKGROUND: Gliomas are the most common malignant brain tumors in children and adults. A subset of these tumors harbour mutations in the enzyme isocitrate dehydrogenase (IDH) which produces the novel oncometabolite 2-hydroxyglutarate (2HG). In general, patients with an IDH mutant glioma have a longe...
Autores principales: | Nguyen, Thanh, Melkus, Gerd, Taccone, Michael, Ghinda, Diana, Torres, Carlos, Zakhari, Nader, Woulfe, John, Jansen, Gerrard, Cameron, Ian, Moldovan, Ioana, Alkherayf, Fahad |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715783/ http://dx.doi.org/10.1093/neuonc/noaa222.356 |
Ejemplares similares
-
Isocitrate dehydrogenase mutations in myeloid malignancies
por: Medeiros, B C, et al.
Publicado: (2017) -
Identification of medicinal compounds as potential inhibitors for mutated isocitrate dehydrogenases against chondrosarcoma
por: Shah, Fahad Hassan, et al.
Publicado: (2022) -
Mutation of Isocitrate Dehydrogenase 1 in Cholangiocarcinoma Impairs Tumor Progression by Inhibiting Isocitrate Metabolism
por: Su, Li, et al.
Publicado: (2020) -
Isocitrate dehydrogenase inhibitors in acute myeloid leukemia
por: Liu, Xiaoyan, et al.
Publicado: (2019) -
The Role of Isocitrate Dehydrogenases in Direct Reprogramming to Cardiomyocytes
por: Ishida, Tomoaki, et al.
Publicado: (2021)