MODL-24. AN ORGANOTYPIC CHUNK CULTURE TECHNIQUE TO STUDY DISEASE MECHANISM AND DEVELOP TARGETED THERAPEUTICS FOR PEDIATRIC ADAMANTINOMATOUS CRANIOPHARYNGIOMA

BACKGROUND: Advances in the treatment of Adamantinomatous Craniopharyngioma (ACP) face challenges with translation to clinical study due to the absence of robust culture models of the disease. We developed a technique for culturing human ACP tissue in an organotypic chunk culture format that retains...

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Detalles Bibliográficos
Autores principales: Vijmasi, Trinka, Prince, Eric, Hengartner, Astrid, Staulcup, Susan, Griesinger, Andrea, Donson, Andrew, Gilani, Ahmed, Foreman, Nicholas, Hankinson, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Preclinical Models/Experimental Therapy/Drug Discovery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715791/
http://dx.doi.org/10.1093/neuonc/noaa222.597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715791/
http://dx.doi.org/10.1093/neuonc/noaa222.597

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