Cargando…

DIPG-08. ELECTRONIC SEQUENCING PROVIDES OPTIMIZED QUANTIFICATION OF SERIAL, MULTI-GENE MOLECULAR RESPONSE IN THE CSF OF CHILDREN WITH HIGH-GRADE GLIOMA

BACKGROUND: For pediatric high-grade glioma (pHGG), non-invasive methods for diagnosis and surveillance are needed. Tumors release DNA (tDNA) into cerebrospinal fluid (CSF), allowing for detection of tumor-associated mutations by CSF sampling. We hypothesized that direct, electronic analysis of tDNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Bruzek, Amy, Muruganand, Ashwath, Ravi, Karthik, Wadden, Jack, Babila, Clarissa, Tunkle, Leo, Wierzbicki, Kyle, Stallard, Stefanie, Cantor, Evan, Qin, Tingting, Wolfe, Ian, Mody, Rajen, Muraszko, Karin, Franson, Andrea, Robertson, Patrica, Maher, Cormac, Garton, Hugh, Koschmann, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715796/
http://dx.doi.org/10.1093/neuonc/noaa222.059