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MBRS-03. SINGLE NUCLEUS TRANSCRIPTOME PROFILES FROM HUMAN DEVELOPING CEREBELLUM REVEAL POTENTIAL CELLULAR ORIGINS OF MEDULLOBLASTOMA BRAIN TUMORS

Medulloblastoma (MB) is a highly malignant pediatric brain tumor originating from the cerebellum and brainstem. Identification of molecular subgroups forming this heterogeneous tumor entity was initially achieved from transcriptome characterization and further strengthened using DNA methylation prof...

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Detalles Bibliográficos
Autores principales: Okonechnikov, Konstantin, Sepp, Mari, Leiss, Kevin, Kutscher, Lena, Ernst, Kati, Jones, David, Jäger, Natalie, Pajtler, Kristian W, Kaessmann, Henrik, Pfister, Stefan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715804/
http://dx.doi.org/10.1093/neuonc/noaa222.524