RARE-37. NOONAN SYNDROME AND GLIONEURONAL TUMORS: A CENTRAL NERVOUS SYSTEM CANCER PREDISPOSITION ASSOCIATION?

BACKGROUND: Noonan syndrome (NS) is associated with germline Ras signaling pathway mutations, RAS overactivation and increased tumorigenesis risk. Rosette-forming glioneuronal tumors (RFGT) are rare indolent tumors. We report the molecular profiling of two patients with NS and RFGT. PATIENT 1: A 22-...

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Detalles Bibliográficos
Autores principales: Shatara, Margaret, Varga, Elizabeth A, Boué, Daniel R, Martin, Lisa, Rusin, Jerome A, Rodriguez, Diana P, Jones, Jeremy, McAllister, Aaron, Leonard, Jeffrey R, Pindrik, Jonathan, Schieffer, Kathleen M, Leraas, Kristen M, Lichtenberg, Tara M, Mardis, Elaine R, Cottrell, Catherine E, Osorio, Diana S, AbdelBaki, Mohamed S, Finlay, Jonathan L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Craniopharyngioma and Rare Tumors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715866/
http://dx.doi.org/10.1093/neuonc/noaa222.747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715866/
http://dx.doi.org/10.1093/neuonc/noaa222.747

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