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MBCL-04. 5 – AZACYTIDINE IN TREATMENT OF CHILDREN WITH DE NOVO AND RELAPSED METASTATIC MEDULLOBLASTOMA: RESULTS OF INTERCENTER PILOT STUDY

The aim of this study was to estimate treatment toxicity and event-free survival (EFS) according to therapeutic program, MYC/MYC-N gene amplification and MGMT/DNMT (1, 3a, 3b) proteins expression in tumor cells. From 2016 to 2018 twenty four patients were included in trial. Children underwent adjuva...

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Detalles Bibliográficos
Autores principales: Levashov, Andrey, Khochenkov, Dmitry, Stroganova, Anna, Ryzhova, Marina, Gorelyshev, Sergey, Kadirov, Shavkat, Zagidullina, Svetlana, Babelyan, Stepan, Subbotina, Natalya, Mentkevich, Georgy, Sidelnikov, Dmitry, Daylidite, Vidmante, Grigorenko, Vasily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715888/
http://dx.doi.org/10.1093/neuonc/noaa222.480