ETMR-18. TARGETING Lin28 IN ETMR WITH ODC1 INHIBITOR DFMO

Embryonal tumor with multilayered rosettes (ETMR), is an aggressive brain tumor primarily occurring in young patients (<4 years of age) and characterized by C19MC amplification and Lin28 overexpression. These genetic hallmarks have been shown to participate in driving ETMR in a C19MC-Lin28-MYCN c...

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Detalles Bibliográficos
Autores principales: Goodyke, Austin, Kelly, Shannon, Zagorski, Joseph, VanSickle, Elizabeth, Maser, Tyler, Sortwell, Caryl, Kemp, Christopher, Nagulapally, Abhinav, Dykema, Karl, Saulnier-Sholler, Giselle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
ETMR and other Embryonal Tumors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715939/
http://dx.doi.org/10.1093/neuonc/noaa222.221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715939/
http://dx.doi.org/10.1093/neuonc/noaa222.221

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