TBIO-15. MODELING DEVELOPMENTAL GENE EXPRESSION DYNAMICS AT CELLULAR RESOLUTION TO INTERPRET PEDIATRIC BRAIN TUMOR TRANSCRIPTIONAL PROGRAMS

A central challenge in understanding the biology of pediatric brain tumors is defining the cellular and molecular context where oncogenesis occurs. We hypothesize that spatiotemporally restricted cell types are uniquely susceptible to specific genetic alterations, which alter normal neurodevelopment...

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Detalles Bibliográficos
Autores principales: Jessa, Selin, Kabir, Nisha, Vladoiu, Maria, Hébert, Steven, Taylor, Michael D, Jabado, Nada, Kleinman, Claudia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Tumor Biology (not fitting a specific disease category)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715983/
http://dx.doi.org/10.1093/neuonc/noaa222.842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715983/
http://dx.doi.org/10.1093/neuonc/noaa222.842

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