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Knocking down TRPM2 expression reduces cell injury and NLRP3 inflammasome activation in PC12 cells subjected to oxygen-glucose deprivation

Transient receptor potential melastatin 2 (TRPM2) is an important ion channel that represents a potential target for treating injury caused by cerebral ischemia. However, it is unclear whether reducing TRPM2 expression can help repair cerebral injury, and if so what the mechanism underlying this pro...

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Detalles Bibliográficos
Autores principales: Pan, Tao, Zhu, Qiu-Jiao, Xu, Li-Xiao, Ding, Xin, Li, Jian-Qin, Sun, Bin, Hua, Jun, Feng, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716023/
https://www.ncbi.nlm.nih.gov/pubmed/32394974
http://dx.doi.org/10.4103/1673-5374.282271