Amyloid-beta peptide neurotoxicity in human neuronal cells is associated with modulation of insulin-like growth factor transport, lysosomal machinery and extracellular matrix receptor interactions

Extracellular deposits of the amyloid-beta peptide (Aβ) are known as the main pathological hallmark of Alzheimer’s disease. In Alzheimer’s disease, neurons are injured and die throughout the brain, a process in which Aβ neurotoxicity is considered to play an important role. However, the molecular me...

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Detalles Bibliográficos
Autores principales: Deng, Liting, Haynes, Paul A., Wu, Yunqi, Amirkhani, Ardeshir, Kamath, Karthik Shantharam, Wu, Jemma X., Pushpitha, Kanishka, Gupta, Veer, Graham, Stuart, Gupta, Vivek K., Mirzaei, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716038/
https://www.ncbi.nlm.nih.gov/pubmed/32394972
http://dx.doi.org/10.4103/1673-5374.282261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716038/
https://www.ncbi.nlm.nih.gov/pubmed/32394972
http://dx.doi.org/10.4103/1673-5374.282261

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