Human equivalent dose of oral 4-aminopyridine differentiates nerve crush injury from transection injury and improves post-injury function in mice

4-Aminopyridine (4-AP), an FDA-approved drug for the symptomatic treatment of multiple sclerosis, is used to improve neuromuscular function in patients with diverse demyelinating disorders. We recently demonstrated that local, transdermal or injectable forms of 4-AP improve myelination, nerve conduc...

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Detalles Bibliográficos
Autores principales: Hsu, Chia George, Talukder, M A Hassan, Yue, Li, Turpin, Loel C., Noble, Mark, Elfar, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716044/
https://www.ncbi.nlm.nih.gov/pubmed/32394968
http://dx.doi.org/10.4103/1673-5374.280319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716044/
https://www.ncbi.nlm.nih.gov/pubmed/32394968
http://dx.doi.org/10.4103/1673-5374.280319

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