Maternal Microdeletion at the H19/Igf2 ICR in Mice Increases Offspring Susceptibility to In Utero Environmental Perturbation

Deficiency of methyl donor nutrients folate, choline, and methionine (methyl deficiency) during gestation can impair fetal development and perturb DNA methylation. Here, we assessed genetic susceptibility to methyl deficiency by comparing effects in wildtype C57BL/6J (B6) mice to mutant mice carryin...

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Detalles Bibliográficos
Autores principales: Pal, Anandita, Oakes, Judy, Elnagheeb, Marwa, Ideraabdullah, Folami Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Environmental and Nutritional Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716063/
https://www.ncbi.nlm.nih.gov/pubmed/33313480
http://dx.doi.org/10.1177/2516865720970575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716063/
https://www.ncbi.nlm.nih.gov/pubmed/33313480
http://dx.doi.org/10.1177/2516865720970575

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